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NHS Trials Groundbreaking Brain Tumour Test That Could Transform Cancer Care
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Patients may receive faster, more accurate diagnoses thanks to a new DNA sequencing pilot that provides critical tumour information during operations.
The NHS has launched a world-first pilot of a rapid genomic test that could dramatically shorten the time patients wait to learn what type of brain tumour they have. Instead of waiting several weeks for a full diagnosis, patients could receive definitive results within days. In some cases, crucial information may be delivered to surgeons in under two hours while an operation is still taking place.
The test examines the DNA, or genetic code, of a small tumour sample collected during a biopsy or surgery. This creates a detailed biological profile that helps doctors distinguish between the many different types of brain tumour, which can range from slow-growing conditions to highly aggressive cancers. Knowing the precise type is essential because tumours can respond differently to surgery, chemotherapy and radiotherapy.
The groundbreaking technology could help deliver diagnoses in hours rather than weeks, giving patients faster answers and helping doctors begin personalised treatment sooner. Read more on the NHS website.
For some patients, the findings could help surgeons decide how much of a tumour can be safely removed without causing unnecessary damage to healthy brain tissue. A faster and more accurate diagnosis may also allow treatment to begin sooner and help patients enter suitable clinical trials, some of which require detailed genetic information before a person can participate. More than a quarter of patients currently wait over a month after surgery to discover which type of brain tumour they have.
Developed by scientists and clinicians at the University of Nottingham and Nottingham University Hospitals NHS Trust, the technology will initially be introduced at five specialist centres in Nottingham, Birmingham, London and Newcastle before being expanded further across England. NHS leaders say the pilot will gather evidence to determine whether rapid genomic testing can eventually become part of routine care, offering patients faster answers, more personalised treatment and less time spent living with uncertainty.